84573-33-1
84573-33-1
Chemical Structure
Quinocarcin
Synonym(s): Quinocarmycin; DC-52; KW2152 free base
- CAS No.: 84573-33-1
- Formula:C18H22N2O4
- Molecular Weight:330.38
IUPAC Name: (2aS,3R,5S,6S,6aR,11bS)-11-methoxy-12-methyl-2a,3,4,5,6,6a,7,11b-octahydro-1H-2-oxa-2a1,12-diaza-3,6-methanonaphtho[1,2,3-cd]azulene-5-carboxylic acid
InChIKey: VOUMVHRRAVBACH-MQZHMRIFSA-N
SMILES: O=C(O)[C@@H]1[C@]2([C@]([H])(N3[C@@]4(CO[C@]3([C@@]([H])(C1)N2C)[H])[H])CC5=C4C(OC)=CC=C5)[H]
Biological Activity: Quinocarcin (DC-52) is a potent antitumor antibiotic. Quinocarcin inhibits Bacillus subtilis DNA, RNA and protein syntheses[1][2].
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Quinocarcin | Quinocarcin (DC-52) is a potent antitumor antibiotic. Quinocarcin inhibits Bacillus subtilis DNA, RNA and protein syntheses. | |||||||||||||||||||||
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References
- [1]. Tomita F, et al. Quinocarcin, a novel antitumor antibiotic. 3. Mode of action. J Antibiot (Tokyo). 1984 Oct;37(10):1268-72. [Content Brief]
- [2]. Kahsai AW, et al. Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44. Chem Biol. 2006 Sep;13(9):973-83. [Content Brief]
Keywords
