847499-27-8
847499-27-8
Chemical Structure
Delanzomib
Synonym(s): CEP-18770
- CAS No.: 847499-27-8
- Formula:C21H28BN3O5
- Molecular Weight:413.28
IUPAC Name: ((R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutyl)boronic acid
InChIKey: SJFBTAPEPRWNKH-CCKFTAQKSA-N
SMILES: CC(C)C[C@@H](B(O)O)NC([C@@H](NC(C1=NC(C2=CC=CC=C2)=CC=C1)=O)[C@H](O)C)=O
Biological Activity: Delanzomib (CEP-18770) is a potent and orally active chymotrypsin-like activity of the proteasome inhibitor with an IC50 of 3.8 nM. Delanzomib inhibits NF-κB activity, induces cancer cell apoptotic, and has strong antiangiogenic and anti-cancer activities[1].
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Delanzomib | 98.0% | Delanzomib (CEP-18770) is a potent and orally active chymotrypsin-like activity of the proteasome inhibitor with an IC50 of 3.8 nM. Delanzomib inhibits NF-κB activity, induces cancer cell apoptotic, and has strong antiangiogenic and anti-cancer activities. | ||||||||||||||||||||
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