84777-85-5
Chemical Structure
Virustomycin A
- CAS No.: 84777-85-5
- Formula:C48H71NO14
- Molecular Weight:886.08
IUPAC Name: (2R,4R,5S,6R)-2-((2S,3R,4S)-4-((2R,3S,4E,6E,9R,10S,11S,12R,13R,14E,16Z)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen-2-yl)-3-hydroxypentan-2-yl)-2-hydroxy-5-methyl-6-((E)-prop-1-en-1-yl)tetrahydro-
InChIKey: YIKWIQAIKGWYCF-ACOKZJPPSA-N
SMILES: O=C(O[C@@H]1C[C@](O)([C@@H](C)[C@H](O)[C@@H]([C@H]([C@@H](OC)/C=C/C=C(C)/C[C@@H](C)[C@H](O)[C@H](CC)[C@H](O)[C@H](C)/C=C(C)/C=C2\OC)OC2=O)C)O[C@H](/C=C/C)[C@H]1C)/C=C/C(NC3=C(O)CCC3=O)=O
Biological Activity: Virustomycin A is a nature product that could be isolated from Streptomyces. Virustomycin A has selective and potent antitrypanosomal activity[1][2].
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Virustomycin A | Virustomycin A is a nature product that could be isolated from Streptomyces. Virustomycin A has selective and potent antitrypanosomal activity. | |||||||||||||||||||||
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- [1]. Otoguro K, et, al. Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites. J Antibiot (Tokyo). 2008 Jun;61(6):372-8. [Content Brief]
- [2]. Nara A, et, al. Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms. J Antibiot (Tokyo). 2017 May;70(5):616-624. [Content Brief]
Keywords
