850859-24-4
Chemical Structure
LyP-2
- CAS No.: 850859-24-4
- Formula:C37H69N17O12S2
- Molecular Weight:1008.18
IUPAC Name: (2R,5S,8S,11S,17S,20S)-20-((S)-2-((R)-2-amino-3-mercaptopropanamido)-5-guanidinopentanamido)-8-(4-aminobutyl)-11-(3-guanidinopropyl)-2-(mercaptomethyl)-5,17-dimethyl-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazatricosanedioic acid
InChIKey: QCDJYHWNVUMOBT-DSQOZMABSA-N
SMILES: O=C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(NCC(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N
Biological Activity: LyP-2 is a peptide that homes to tumor lymphatics. LyP2 homes to lymphatics of C8161 melanomas and cervical carcinomas and K14-HPV16 skin, but not to MDA-MB435 tumors, showing heterogeneity in the molecular markers of tumor cells and lymphatics[1].
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LyP-2 | LyP-2 is a peptide that homes to tumor lymphatics. LyP2 homes to lymphatics of C8161 melanomas and cervical carcinomas and K14-HPV16 skin, but not to MDA-MB435 tumors, showing heterogeneity in the molecular markers of tumor cells and lymphatics. | |||||||||||||||||||||
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Keywords
