85280-90-6
Chemical Structure
15(S)-15-methyl Prostaglandin D2
Synonym(s): 15(S)-15-Methyl PGD2
- CAS No.: 85280-90-6
- Formula:C21H34O5
- Molecular Weight:366.49
IUPAC Name: (Z)-7-((1R,2R,5S)-5-hydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)-3-oxocyclopentyl)hept-5-enoic acid
InChIKey: CTXLUMAOXBULOZ-QEQARHSSSA-N
SMILES: OC(CCC/C=C\C[C@@H]([C@H](C1)O)[C@H](C1=O)/C=C/[C@@](C)(O)CCCCC)=O
Biological Activity: 15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation. It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2).
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15(S)-15-methyl Prostaglandin D2 | 15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation. It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2). | |||||||||||||||||||||
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