85483-00-7
85483-00-7
Chemical Structure
3-Deoxyaphidicolin
- CAS No.: 85483-00-7
- Formula:C20H34O3
- Molecular Weight:322.48
IUPAC Name: ((4R,4aR,6aS,8R,9R,11aS,11bS)-9-hydroxy-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-4,9-diyl)dimethanol
InChIKey: VHWTVINEPPOCLA-DTMQFJJTSA-N
SMILES: OC[C@@]1(C)[C@]2([H])CC[C@](C[C@@](C3)([H])[C@](CO)(O)CC4)([H])[C@]43[C@@]2(C)CCC1
Biological Activity: 3-Deoxyaphidicolin exhibits phytotoxic efficacy, that inhibits root growth of lettuce seedlings. 3-Deoxyaphidicolin also exhibits leishmanicidal activity against Leishmania major and Leishmania braziliensis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Deoxyaphidicolin | 3-Deoxyaphidicolin exhibits phytotoxic efficacy, that inhibits root growth of lettuce seedlings. 3-Deoxyaphidicolin also exhibits leishmanicidal activity against Leishmania major and Leishmania braziliensis. | |||||||||||||||||||||
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References
- [1]. Haraguchi T, et al., Specific inhibitors of eukaryotic DNA synthesis and DNA polymerase alpha, 3-deoxyaphidicolin and aphidicolin-17-monoacetate. Nucleic Acids Res. 1983 Feb 25;11(4):1197-209. [Content Brief]
- [2]. Santos G B, et al., The semisynthetic landscape of aphidicolin: inspiration towards leishmanicidal compounds[J]. Journal of the Brazilian Chemical Society, 2014, 25: 1885-1899.
