855170-53-5
855170-53-5
Chemical Structure
ND-7001
- CAS No.: 855170-53-5
- Formula:C24H21N3O3
- Molecular Weight:399.45
IUPAC Name: 3-(8-methoxy-1-methyl-2-oxo-7-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl)benzamide
InChIKey: WYTGWTBNDXWMMB-UHFFFAOYSA-N
SMILES: O=C(N)C1=CC=CC(=C1)C2=NCC(=O)N(C=3C=C(OC)C(=CC23)C=4C=CC=CC4)C
Biological Activity: ND-7001 is an inhibitor of PDE2 with an IC50 of 0.05 μM. ND-7001 exhibits good selectivity agianst PDE3 and PDE4. ND-7001 increases cGMP levels in primary neuronal cultures of rat cerebral cortical neurons. ND-7001 displays anxiolytic effects[1].
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ND-7001 | ND-7001 is an inhibitor of PDE2 with an IC50 of 0.05 μM. ND-7001 exhibits good selectivity agianst PDE3 and PDE4. ND-7001 increases cGMP levels in primary neuronal cultures of rat cerebral cortical neurons. ND-7001 displays anxiolytic effects. | |||||||||||||||||||||
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References
Keywords
