857402-23-4
Chemical Structure
Retaspimycin
- CAS No.: 857402-23-4
- Formula:C31H45N3O8
- Molecular Weight:587.70
IUPAC Name: (4E,6E,8S,9S,10E,12S,13R,14S,16R)-14-(allylamino)-12,15,13-trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-2-aza-1(1,3)-benzenacycloheptadecaphane-4,6,10-trien-9-yl carbamate
InChIKey: OAKGNIRUXAZDQF-HTLBVUBBSA-N
SMILES: OC1=C(C[C@H](C[C@@H]([C@@H]2O)OC)C)C(NCC=C)=C(C=C1NC(/C(C)=C/C=C/[C@@H]([C@H](/C(C)=C/[C@@H]2C)OC(N)=O)OC)=O)O
Biological Activity: Retaspimycin is a potent inhibitor of Hsp90, with EC50s of 119 nM for both Hsp90 and Grp9.
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Retaspimycin | Retaspimycin is a potent inhibitor of Hsp90, with EC50s of 119 nM for both Hsp90 and Grp9. | |||||||||||||||||||||
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Keywords