863564-16-3
863564-16-3
Chemical Structure
HSD17B13-IN-7
- CAS No.: 863564-16-3
- Formula:C21H24FNO4
- Molecular Weight:373.42
InChIKey: HYQPPDQRUHLNQQ-WEHONNDLSA-N
SMILES: FC1=C(O)C=CC(C(NC[C@]2(O)CC[C@H](COC3=CC=CC=C3)CC2)=O)=C1
Biological Activity: HSD17B13-IN-7 (compound 1), a fluorophenol-containing compound, is a potent HSD17B13 inhibitor with IC50s of 0.18 μM and 0.25 μM β-estradiol and Leukotriene B4 as substrates, respectively. HSD17B13-IN-7 is a potent N-methyl-D-aspartate (NMDA) NR2B receptor antagonist. HSD17B13-IN-7 has the potential for non-alcoholic fatty liver disease research[1].
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HSD17B13-IN-7 | HSD17B13-IN-7 (compound 1), a fluorophenol-containing compound, is a potent HSD17B13 inhibitor with IC50s of 0.18 μM and 0.25 μM β-estradiol and Leukotriene B4 as substrates, respectively. HSD17B13-IN-7 is a potent N-methyl-D-aspartate (NMDA) NR2B receptor antagonist. HSD17B13-IN-7 has the potential for non-alcoholic fatty liver disease research. | |||||||||||||||||||||
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References
Keywords
