864420-54-2

NAE-IN-M22 Chemical Structure
864420-54-2

Chemical Structure

NAE-IN-M22

  • CAS No.: 864420-54-2
  • Formula:C20H24Cl2N2
  • Molecular Weight:363.32

IUPAC Name: 1-benzyl-N-(2,4-dichlorophenethyl)piperidin-4-amine

InChIKey: WMEXQHGRMWPOEF-UHFFFAOYSA-N

SMILES: ClC1=CC=C(CCNC2CCN(CC3=CC=CC=C3)CC2)C(Cl)=C1

Biological Activity: NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo[1].

Cat. No. Product Name Purity Description Pricing
HY-115537 		NAE-IN-M22 99.94% NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.
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