864420-54-2
864420-54-2
Chemical Structure
NAE-IN-M22
- CAS No.: 864420-54-2
- Formula:C20H24Cl2N2
- Molecular Weight:363.32
IUPAC Name: 1-benzyl-N-(2,4-dichlorophenethyl)piperidin-4-amine
InChIKey: WMEXQHGRMWPOEF-UHFFFAOYSA-N
SMILES: ClC1=CC=C(CCNC2CCN(CC3=CC=CC=C3)CC2)C(Cl)=C1
Biological Activity: NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NAE-IN-M22 | 99.94% | NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo. | ||||||||||||||||||||
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