86580-77-0
Chemical Structure
BRL 34778
- CAS No.: 86580-77-0
- Formula:C23H27ClFN3O2
- Molecular Weight:431.93
IUPAC Name: 4-amino-5-chloro-N-((1R,3s,5S)-9-(4-fluorobenzyl)-9-azabicyclo[3.3.1]nonan-3-yl)-2-methoxybenzamide
InChIKey: PSOJUYFGYMSZHW-NNZMDNLPSA-N
SMILES: O=C(C1=C(C=C(N)C(Cl)=C1)OC)N[C@@H](C[C@@H]2CCC3)C[C@@H]3N2CC4=CC=C(F)C=C4
Biological Activity: BRL 34778 is a potent, selective and orally active dopamine D2 receptor antagonist with a Ki of 2.14 nM. BRL 34778 exhibits antipsychotic activity with low activity for extrapyramidal effects and sedation. BRL 34778 can be used for the research of neurological disease, such as schizophrenia[1].
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BRL 34778 | BRL 34778 is a potent, selective and orally active dopamine D2 receptor antagonist with a Ki of 2.14 nM. BRL 34778 exhibits antipsychotic activity with low activity for extrapyramidal effects and sedation. BRL 34778 can be used for the research of neurological disease, such as schizophrenia. | |||||||||||||||||||||
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Keywords
