870640-61-2
870640-61-2
Chemical Structure
Monomethyl auristatin E intermediate-12
- CAS. Nr.: 870640-61-2
- Formula:C16H27NO2
- Molecular Weight:265.39
IUPAC Name: (2S,3S)-N-benzyl-1,1-dimethoxy-N,3-dimethylpentan-2-amine
InChIKey: GYOWFCNRTAPUGL-ZFWWWQNUSA-N
SMILES: CN(CC1=CC=CC=C1)[C@H](C(OC)OC)[C@@H](C)CC
Biological Activity: Monomethyl auristatin E intermediate-12 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
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Monomethyl auristatin E intermediate-12 | Monomethyl auristatin E intermediate-12 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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