870710-02-4
Chemical Structure
BVT-116429
- CAS No.: 870710-02-4
- Formula:C13H12F4N2OS
- Molecular Weight:320.31
IUPAC Name: (S)-2-(((S)-1-(2-fluorophenyl)ethyl)amino)-5-methyl-5-(trifluoromethyl)thiazol-4(5H)-one
InChIKey: KNHNFKZUNFPPQE-MADCSZMMSA-N
SMILES: C[C@@H](C1=C(C=CC=C1)F)NC(S[C@@](C)2C(F)(F)F)=NC2=O
Biological Activity: BVT-116429 is an 11βHSD1 inhibitor with the activity of increasing adiponectin concentration and improving glucose homeostasis in diabetic mice. BVT-116429 can increase plasma adiponectin levels in diabetic KKAy mice, reduce basal insulin levels, and reduce fasting blood glucose levels after 10 days of inhibition, similar to the effect of rosiglitazone.
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BVT-116429 | BVT-116429 is an 11βHSD1 inhibitor with the activity of increasing adiponectin concentration and improving glucose homeostasis in diabetic mice. BVT-116429 can increase plasma adiponectin levels in diabetic KKAy mice, reduce basal insulin levels, and reduce fasting blood glucose levels after 10 days of inhibition, similar to the effect of rosiglitazone. | |||||||||||||||||||||
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Keywords
