872188-59-5
Chemical Structure
Cys-Gly-3M3SH
- CAS No.: 872188-59-5
- Formula:C12H24N2O4S
- Molecular Weight:292.39
IUPAC Name: S-(1-hydroxy-3-methylhexan-3-yl)-L-cysteinylglycine
InChIKey: FIKNGFBNGIHRJV-QHGLUPRGSA-N
SMILES: C(SC[C@@H](C(NCC(O)=O)=O)N)(CCC)(CCO)C
Biological Activity: Cys-Gly-3M3SH is an odorless thiol precursor dipeptide and the major secreted precursor of the human axillary odorant 3M3SH, which forms thiol body odor after biotransformation by the skin microbiota. Cys-Gly-3M3SH is biotransformed into 3M3SH by certain staphylococci. Cys-Gly-3M3SH is actively taken up by bacteria via a secondary transport system dependent on the proton motive force. Cys-Gly-3M3SH is used in research related to osmidrosis and skin diseases[1][2].
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Cys-Gly-3M3SH | Cys-Gly-3M3SH is an odorless thiol precursor dipeptide and the major secreted precursor of the human axillary odorant 3M3SH, which forms thiol body odor after biotransformation by the skin microbiota. Cys-Gly-3M3SH is biotransformed into 3M3SH by certain staphylococci. Cys-Gly-3M3SH is actively taken up by bacteria via a secondary transport system dependent on the proton motive force. Cys-Gly-3M3SH is used in research related to osmidrosis and skin diseases. | |||||||||||||||||||||
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References
- [1]. Emter R, et al. The sequential action of a dipeptidase and a beta-lyase is required for the release of the human body odorant 3-methyl-3-sulfanylhexan-1-ol from a secreted Cys-Gly-(S) conjugate by Corynebacteria. The Journal of biological chemistry. 2008 Jul 25;283(30):20645-52.
- [2]. Bawdon D, et al. Identification of axillary Staphylococcus sp. involved in the production of the malodorous thioalcohol 3-methyl-3-sufanylhexan-1-ol. FEMS microbiology letters. 2015 Aug;362(16):fnv111.
