875898-41-2
875898-41-2
Chemical Structure
NMDA receptor antagonist 2
- CAS No.: 875898-41-2
- Formula:C20H21N7O
- Molecular Weight:375.43
IUPAC Name: N-((1S,3S)-3-(3-(4-methylbenzyl)-1,2,4-oxadiazol-5-yl)cyclopentyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChIKey: JTKNIJDRSHYXLX-GJZGRUSLSA-N
SMILES: CC1=CC=C(CC2=NOC([C@@H]3C[C@@H](NC4=C5C(NN=C5)=NC=N4)CC3)=N2)C=C1
Biological Activity: NMDA receptor antagonist 2 is a potent and orally active NR2B subtype-selective NMDA antagonist with an IC50 and a Ki of 1.0 nM and 0.88 nM, respectively. NMDA receptor antagonist 2 is used for the study of neuropathic pain and Parkinson’s disease[1].
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NMDA receptor antagonist 2 | NMDA receptor antagonist 2 is a potent and orally active NR2B subtype-selective NMDA antagonist with an IC50 and a Ki of 1.0 nM and 0.88 nM, respectively. NMDA receptor antagonist 2 is used for the study of neuropathic pain and Parkinson’s disease. | |||||||||||||||||||||
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References
Keywords
