878022-36-7
Chemical Structure
NU-8231
- CAS No.: 878022-36-7
- Formula:C26H26ClNO5
- Molecular Weight:467.95
IUPAC Name: 3-(4-chlorophenyl)-3-((4-hydroxy-3,5-dimethoxybenzyl)oxy)-2-propylisoindolin-1-one
InChIKey: NDIKZCQEKGERHF-UHFFFAOYSA-N
SMILES: O=C1C=2C=CC=CC2C(OCC3=CC(OC)=C(O)C(OC)=C3)(C4=CC=C(Cl)C=C4)N1CCC
Biological Activity: NU-8231 (Compound 2) is a p53-MDM2 binding inhibitor with an IC50 of 5.3-200 μM for inhibiting the p53-MDM2 interaction. NU-8231 is applicable for cancer research[1].
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NU-8231 | NU-8231 (Compound 2) is a p53-MDM2 binding inhibitor with an IC50 of 5.3-200 μM for inhibiting the p53-MDM2 interaction. NU-8231 is applicable for cancer research. | |||||||||||||||||||||
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Keywords