878415-59-9
878415-59-9
Chemical Structure
XS018661
- CAS No.: 878415-59-9
- Formula:C22H24N4O3
- Molecular Weight:392.46
IUPAC Name: methyl 4-((2-(piperidin-1-ylmethyl)-1H-benzo[d]imidazol-6-yl)carbamoyl)benzoate
InChIKey: UVAMTJLXRMVTBI-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC=C(C=C1)C(=O)NC=2C=CC=3N=C(NC3C2)CN4CCCCC4
Biological Activity: XS018661 is a dual inhibitor of the YEATS domains of ENL and its paralog AF9 with IC50 values of 1.6 and 3 μM as well as Kd values of 754 nM and 523 nM, respectively[1].
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XS018661 | XS018661 is a dual inhibitor of the YEATS domains of ENL and its paralog AF9 with IC50 values of 1.6 and 3 μM as well as Kd values of 754 nM and 523 nM, respectively. | |||||||||||||||||||||
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References
Keywords
