88017-05-4
Chemical Structure
H142/08
- CAS No.: 88017-05-4
- Formula:C22H37N3O6
- Molecular Weight:439.55
InChIKey: SYEJZNWACSPJHS-UHFFFAOYSA-N
SMILES: O=C(N1CCOCC1)NCCNCC(COC2=CC=C(C=C2)OCCOCC(C)C)O
Biological Activity: H142/08 is a β1-adrenergic receptor-selective agonist. H142/08 induces concentration-dependent relaxation of isolated rat uterus and acts as a chronotropic stimulant to increase atrial rate, and its effects are effectively antagonized by Pafenolol (HY-165495). H142/08 also antagonizes the chronotropic effect of isoproterenol on isolated rat right atrium, but requires a higher proportion of receptor occupancy to produce sufficient stimulatory effects[1].
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H142/08 | H142/08 is a β1-adrenergic receptor-selective agonist. H142/08 induces concentration-dependent relaxation of isolated rat uterus and acts as a chronotropic stimulant to increase atrial rate, and its effects are effectively antagonized by Pafenolol (HY-165495). H142/08 also antagonizes the chronotropic effect of isoproterenol on isolated rat right atrium, but requires a higher proportion of receptor occupancy to produce sufficient stimulatory effects. | |||||||||||||||||||||
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Keywords
