882268-09-9
882268-09-9
Chemical Structure
SGM8
- CAS No.: 882268-09-9
- Formula:C12H15NOS2
- Molecular Weight:253.38
IUPAC Name: (E)-5-((dimethylamino)methylene)-3-(methylthio)-6,7-dihydrobenzo[c]thiophen-4(5H)-one
InChIKey: SBORPYWLRSWZTD-SOFGYWHQSA-N
SMILES: O=C1C2=C(SC=C2CCC1=CN(C)C)SC
Biological Activity: SGM8 is a selective HCMV UL44 inhibitor, with an IC50 of 4.5 μM for the interaction between HCMV UL44 and full-length HCMV UL54. SGM8 selectively inhibits UL44-dependent long-strand DNA synthesis, while exerting weak inhibitory effects on UL54-only dependent short-strand DNA synthesis. SGM8 can be used in studies related to cytomegalovirus infection[1].
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SGM8 | SGM8 is a selective HCMV UL44 inhibitor, with an IC50 of 4.5 μM for the interaction between HCMV UL44 and full-length HCMV UL54. SGM8 selectively inhibits UL44-dependent long-strand DNA synthesis, while exerting weak inhibitory effects on UL54-only dependent short-strand DNA synthesis. SGM8 can be used in studies related to cytomegalovirus infection. | |||||||||||||||||||||
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