882737-42-0
882737-42-0
Chemical Structure
Pridopidine hydrochloride
Synonym(s): ACR16 hydrochloride; ASP2314 hydrochloride; FR310826 hydrochloride
- CAS No.: 882737-42-0
- Formula:C15H24ClNO2S
- Molecular Weight:317.87
IUPAC Name: 4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine hydrochloride
InChIKey: YGRHOYQMBLLGEV-UHFFFAOYSA-N
SMILES: O=S(C1=CC(C2CCN(CC2)CCC)=CC=C1)(C)=O.Cl
Biological Activity: Pridopidine (ACR16) hydrochloride, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with Ki between 70 and 80 nM, which is ~100-fold higher than its affinity toward D2R.
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Pridopidine hydrochloride | Pridopidine (ACR16) hydrochloride, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with Ki between 70 and 80 nM, which is ~100-fold higher than its affinity toward D2R. | |||||||||||||||||||||
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