88660-10-0
Chemical Structure
Pipernonaline
- CAS No.: 88660-10-0
- Formula:C21H27NO3
- Molecular Weight:341.44
IUPAC Name: (2E,8E)-9-(benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)nona-2,8-dien-1-one
InChIKey: PKLGRWSJBLGIBF-JMQWPVDRSA-N
SMILES: O=C(N1CCCCC1)/C=C/CCCC/C=C/C2=CC=C(OCO3)C3=C2
Biological Activity: Pipernonaline is a piperine derivative with antiprostate cancer activity. Pipernonaline inhibits the proliferation of androgen-dependent/independent LNCaP/PC-3 prostate cells. Pipernonaline activates caspase-3 and promotes procaspase-3/PARP cleavage. Pipernonaline also mediates reactive oxygen species (ROS) production, increased intracellular Ca(2+), and mitochondrial membrane depolarization[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pipernonaline | 99.30% | Pipernonaline is a piperine derivative with antiprostate cancer activity. Pipernonaline inhibits the proliferation of androgen-dependent/independent LNCaP/PC-3 prostate cells. Pipernonaline activates caspase-3 and promotes procaspase-3/PARP cleavage. Pipernonaline also mediates reactive oxygen species (ROS) production, increased intracellular Ca(2+), and mitochondrial membrane depolarization. | ||||||||||||||||||||
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