88899-22-3
88899-22-3
Chemical Structure
Bz-FVR-AMC
- CAS No.: 88899-22-3
- Formula:C37H43N7O6
- Molecular Weight:681.78
IUPAC Name: sodium 8-((2-aminoethyl)amino)naphthalene-1-sulfonate
InChIKey: QBDRNGBZKAOZHF-OLWNVYNHSA-N
SMILES: CC1=CC(OC2=CC(NC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC(C3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)CCCNC(N)=N)=O)=CC=C12)=O
Biological Activity: Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM-1s-1. The high concentration of BZ-FVR-AMC inhibits the substrate[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bz-FVR-AMC | 99.49% | Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM-1s-1. The high concentration of BZ-FVR-AMC inhibits the substrate. | ||||||||||||||||||||
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References
- [1]. Vasiljeva O, et al. Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett. 2005 Feb 14;579(5):1285-90. [Content Brief]
- [2]. Vasiljeva O, et al. Recombinant human cathepsin H lacking the mini chain is an endopeptidase. Biochemistry. 2003 Nov 25;42(46):13522-8. [Content Brief]
