89019-63-6
89019-63-6
Chemical Structure
Diheptanoyl Thio-PC
- CAS No.: 89019-63-6
- Formula:C22H44NO6PS2
- Molecular Weight:513.69
InChIKey: BNLGHOHOEIJWCJ-UHFFFAOYSA-N
SMILES: C[N+](C)(C)CCOP(OC[C@H](SC(CCCCCC)=O)CSC(CCCCCC)=O)([O-])=O
Biological Activity: Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).1 Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP.
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Diheptanoyl Thio-PC | Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).1 Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP. | |||||||||||||||||||||
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Keywords
