892145-76-5
892145-76-5
Chemical Structure
2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine
- CAS No.: 892145-76-5
- Formula:C9H11FN2O4S
- Molecular Weight:262.26
IUPAC Name: 1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
InChIKey: LBXPACVSMLWUMQ-PXBUCIJWSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@H](F)[C@H](N2C(NC(C=C2)=S)=O)O1
Biological Activity: 2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine | 2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
