892706-90-0
Chemical Structure
N42FTA
- CAS No.: 892706-90-0
- Formula:C13H11ClN4O
- Molecular Weight:274.71
InChIKey: IRHUOSKJHRHZKH-UHFFFAOYSA-N
SMILES: ClC1=CC=C(CNC2=NC(C3=CC=CO3)=NN2)C=C1
Biological Activity: N42FTA is a non-covalent, non-suicidal inhibitor of FabA from Pseudomonas aeruginosa and Escherichia coli, with IC50 values of 3.27 μM and 2.31 μM, respectively. As a natural substrate mimetic, N42FTA blocks the cross-linking between acyl carrier protein and FabA in Escherichia coli. N42FTA shows no significant antibacterial activity due to poor permeability. N42FTA can be used in studies related to Pseudomonas aeruginosa and Escherichia coli infections[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
N42FTA | N42FTA is a non-covalent, non-suicidal inhibitor of FabA from Pseudomonas aeruginosa and Escherichia coli, with IC50 values of 3.27 μM and 2.31 μM, respectively. As a natural substrate mimetic, N42FTA blocks the cross-linking between acyl carrier protein and FabA in Escherichia coli. N42FTA shows no significant antibacterial activity due to poor permeability. N42FTA can be used in studies related to Pseudomonas aeruginosa and Escherichia coli infections. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
