899713-86-1
Chemical Structure
ML348
Synonym(s): GNF-Pf-1127
- CAS No.: 899713-86-1
- Formula:C18H17ClF3N3O3
- Molecular Weight:415.79
IUPAC Name: N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamide
InChIKey: OXKNHBBDOIMFFQ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(F)(F)F)=CC=C1Cl)CN2CCN(C(C3=CC=CO3)=O)CC2
Biological Activity: ML348 (GNF-Pf-1127) is a selective and reversible acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM, and barely inhibits LYPLA2[1].
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ML348 | 99.97% | ML348 (GNF-Pf-1127) is a selective and reversible acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM, and barely inhibits LYPLA2. | ||||||||||||||||||||
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Keywords