903588-41-0
Chemical Structure
Colocynthoside B
- CAS No.: 903588-41-0
- Formula:C42H62O15
- Molecular Weight:806.94
IUPAC Name: (6aR,6bR,8aR,8bR,9S,11S,12aR,13aS,13bS)-5-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-9-hydroxy-11-((E)-3-hydroxy-2-methylprop-1-en-1-yl)-3,3,6b,8a,9,13a-hexamethyl-1,3,6a,6b,8,8a,8b,9,10,11,12a,13,13a,13b-tetradecahydronaphtho[2',1':4,5]indeno[2,1-b]pyran-4,7-dione
InChIKey: BEQDSDZQSKPXIG-VKIDFJQWSA-N
SMILES: C[C@]12[C@]3([C@](C)([C@]4(C(=CC3)C(C)(C)C(=O)C(O[C@H]5[C@H](O[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O)[C@@H](CO)O5)=C4)[H])C(=O)C[C@]1(C)[C@@]7([C@@](C2)(O[C@H](/C=C(/CO)\C)C[C@]7(C)O)[H])[H])[H]
Biological Activity: Colocynthoside B is a cucurbitane-type triterpenoid glycoside that inhibits passive cutaneous anaphylaxis in type I allergy models and inhibits aflatoxin biosynthesis. Colocynthoside B can be used for research on type I allergy[1][2][3][4][5][6].
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Colocynthoside B | Colocynthoside B is a cucurbitane-type triterpenoid glycoside that inhibits passive cutaneous anaphylaxis in type I allergy models and inhibits aflatoxin biosynthesis. Colocynthoside B can be used for research on type I allergy. | |||||||||||||||||||||
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References
- [1]. Yoshikawa M, et al. Bioactive saponins and glycosides. XXVII. Structures of new cucurbitane-type triterpene glycosides and antiallergic constituents from Citrullus colocynthis. Chemical & pharmaceutical bulletin. 2007 Mar;55(3):428-34. [Content Brief]
- [2]. Darwish RS, et al. Comparative metabolomics reveals the cytotoxic and anti-inflammatory discriminatory chemical markers of raw and roasted colocynth fruit (Citrullus colocynthis L.). RSC Adv. 2021;11(59):37049-37062. Published 2021 Nov 17.
- [3]. Degola F, et al. Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts. Toxins (Basel). 2019 May 22;11(5):286.
- [4]. Kapoor M. Citrullus colocynthis an important plant in indian traditional system of medicine. Pharmacognosy Reviews. 2020 Jan 1;14(27):22.
- [5]. Dhakad PK. A review on phytochemical studies and biological potential of Citrullus colocynthis (L.) Schrad (Cucurbitaceae). J Bioeng Biosci. 2017;5(4):55-64.
