905585-60-6
905585-60-6
Chemical Structure
AZD6918
- CAS No.: 905585-60-6
- Formula:C20H20F2N6O
- Molecular Weight:398.41
InChIKey: QRAQXWWNHQMCBH-LBPRGKRZSA-N
SMILES: N#CC1=C(N=C(C(F)=C1)NC2=NNC(OC(C)C)=C2)N[C@@H](C)C3=CC=C(C=C3)F
Biological Activity: AZD6918 is an orally active and selective Trk tyrosine kinase inhibitor. AZD6918 induces cell death as a single agent and attenuates BDNF/TrkB-induced protection from Etoposide (HY-13629) in vitro. AZD6918 can be used for the research of neuroblastoma[1].
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AZD6918 | AZD6918 is an orally active and selective Trk tyrosine kinase inhibitor. AZD6918 induces cell death as a single agent and attenuates BDNF/TrkB-induced protection from Etoposide (HY-13629) in vitro. AZD6918 can be used for the research of neuroblastoma. | |||||||||||||||||||||
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References
Keywords
