90749-32-9
Chemical Structure
Laprafylline
Synonym(s): S 9795
- CAS No.: 90749-32-9
- Formula:C29H36N6O2
- Molecular Weight:500.64
IUPAC Name: 8-(2-(4-benzhydrylpiperazin-1-yl)ethyl)-3-isobutyl-1-methyl-3,9-dihydro-1H-purine-2,6-dione
InChIKey: OEHQNUNEMMXGRU-UHFFFAOYSA-N
SMILES: CC(C)CN1C2=C(C(N(C)C1=O)=O)N=C(CCN3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3)N2
Biological Activity: Laprafylline (S 9795), a xanthine derivative, is a bronchodilator. Laprafylline has potent anti-bronchoconstrictive effects, inhibiting action on mast cell degranulation and phosphodiesterase (PDE) activity (IC50 of 6 μM)[1].
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Laprafylline | Laprafylline (S 9795), a xanthine derivative, is a bronchodilator. Laprafylline has potent anti-bronchoconstrictive effects, inhibiting action on mast cell degranulation and phosphodiesterase (PDE) activity (IC50 of 6 μM). | |||||||||||||||||||||
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Keywords