910482-46-1
Chemical Structure
Cy5.5-SE potassium
Synonym(s): Cyanine5.5 NHS ester potassium
- CAS No.: 910482-46-1
- Formula:C45H44K3N3O16S4
- Molecular Weight:1128.40
IUPAC Name: 2-((1E,3E,5E)-5-(3-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-1,1-dimethyl-6,8-disulfo-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-3-ethyl-1,1-dimethyl-8-sulfo-1H-benzo[e]indol-3-ium-6-sulfonate, potassium salt
InChIKey: PLNVPANOTGFOKU-UHFFFAOYSA-K
SMILES: O=C(CCCCCN1C2=CC=C3C(C=C(S(=O)(O[K])=O)C=C3S(=O)(O[K])=O)=C2C(C)(C)/C1=C\C=C\C=C\C4=[N+](CC)C5=C(C4(C)C)C(C=C(S(=O)(O[K])=O)C=C6S(=O)([O-])=O)=C6C=C5)ON7C(CCC7=O)=O
Biological Activity: Cy5.5-SE (Cyanine5.5 NHS ester) potassium is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[1][2].
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Cy5.5-SE potassium | Cy5.5-SE (Cyanine5.5 NHS ester) potassium is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance. | |||||||||||||||||||||
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- [1]. Zhu S, et al. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. J Drug Target. 2015 Apr;23(3):257-65. [Content Brief]
- [2]. Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108. [Content Brief]
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