91188-00-0
91188-00-0
Chemical Structure
Merafloxacin
Synonym(s): CI-934
- CAS No.: 91188-00-0
- Formula:C19H23F2N3O3
- Molecular Weight:379.40
IUPAC Name: 1-ethyl-7-(3-((ethylamino)methyl)pyrrolidin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChIKey: BAYYCLWCHFVRLV-UHFFFAOYSA-N
SMILES: O=C(C1=CN(CC)C2=C(C=C(F)C(N3CC(CNCC)CC3)=C2F)C1=O)O
Biological Activity: Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses. Merafloxacin exhibits in vitro activity against gram-positive and gram-negative bacteria[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Merafloxacin | 98.32% | Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses. Merafloxacin exhibits in vitro activity against gram-positive and gram-negative bacteria. | ||||||||||||||||||||
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References
- [1]. Sun Y, et, al. Restriction of SARS-CoV-2 Replication by Targeting Programmed -1 Ribosomal Frameshifting In Vitro. bioRxiv. 2020 Oct 21;2020.10.21.349225. [Content Brief]
- [2]. Mandell W, et, al. In vitro activity of CI-934, a new quinolone, compared with that of other quinolones and other antimicrobial agents. Antimicrob Agents Chemother. 1986 May;29(5):852-7. [Content Brief]
Keywords
