915720-21-7
915720-21-7
Chemical Structure
AZ-23
Synonym(s): AZD1332
- CAS No.: 915720-21-7
- Formula:C17H19ClFN7O
- Molecular Weight:391.83
IUPAC Name: (S)-5-chloro-N2-(1-(5-fluoropyridin-2-yl)ethyl)-N4-(5-isopropoxy-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
InChIKey: LBVKEEFIPBQIMD-JTQLQIEISA-N
SMILES: CC(OC1=CC(NC2=NC(N[C@H](C3=NC=C(F)C=C3)C)=NC=C2Cl)=NN1)C
Biological Activity: AZ-23 is an ATP-competitive and orally bioavailable Trk kinase A/B/C inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZ-23 | 98.92% | AZ-23 is an ATP-competitive and orally bioavailable Trk kinase A/B/C inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively. | ||||||||||||||||||||
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Keywords
