915763-27-8
Chemical Structure
WAY-362692
- CAS No.: 915763-27-8
- Formula:C28H35F3N4O6S2
- Molecular Weight:644.73
IUPAC Name: (S)-N-(tert-butyl)-2-(4-((5-(phenylsulfonyl)-2-(trifluoromethyl)phenyl)sulfonamido)piperidine-1-carbonyl)pyrrolidine-1-carboxamide
InChIKey: IVGIETSLCFMRPI-QHCPKHFHSA-N
SMILES: O=C(N1[C@H](C(N2CCC(NS(=O)(C3=CC(S(=O)(C4=CC=CC=C4)=O)=CC=C3C(F)(F)F)=O)CC2)=O)CCC1)NC(C)(C)C
Biological Activity: WAY-362692 is a secreted frizzled-related protein (sFRP-1) inhibitor (IC50 of 0.02 μM), targeting the netrin domain of sFRP-1. WAY-362692 can competitively inhibit the interaction between sFRP-1 and Wnt proteins, and activate the Wnt/β-catenin signaling pathway (EC50 = 0.03 μM). WAY-362692 can activate osteoblasts and promote bone remodeling. WAY-362692 can be used for the research of metabolic disease, such as osteoporosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
WAY-362692 | 99.91% | WAY-362692 is a secreted frizzled-related protein (sFRP-1) inhibitor (IC50 of 0.02 μM), targeting the netrin domain of sFRP-1. WAY-362692 can competitively inhibit the interaction between sFRP-1 and Wnt proteins, and activate the Wnt/β-catenin signaling pathway (EC50 = 0.03 μM). WAY-362692 can activate osteoblasts and promote bone remodeling. WAY-362692 can be used for the research of metabolic disease, such as osteoporosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
