917909-71-8
917909-71-8
Chemical Structure
BIT-225
- CAS No.: 917909-71-8
- Formula:C16H15N5O
- Molecular Weight:293.32
IUPAC Name: N-carbamimidoyl-5-(1-methyl-1H-pyrazol-4-yl)-2-naphthamide
InChIKey: WVROWPPEIMRGAB-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CC=CC(C3=CN(C)N=C3)=C2C=C1)NC(N)=N
Biological Activity: BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BIT-225 | 98.87% | BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM). | ||||||||||||||||||||
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BIT-225 (Standard) | ≥98% | BIT-225 (Standard) is the analytical standard of BIT-225 (HY-106282). This product is intended for research and analytical applications. BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM). | ||||||||||||||||||||
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References
Keywords
