918505-61-0
918505-61-0
Chemical Structure
BRAF inhibitor
- CAS No.: 918505-61-0
- Formula:C22H18F2N4O3S
- Molecular Weight:456.47
IUPAC Name: N-(2,4-difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)phenyl)propane-2-sulfonamide
InChIKey: SUNCACOTKLUNHD-UHFFFAOYSA-N
SMILES: CC(C)S(=O)(NC1=CC=C(C(C(C2=CNC3=NC=C(C=C32)C4=CC=CN=C4)=O)=C1F)F)=O
Biological Activity: BRAF inhibitor (Compound P-0850) is a B-Raf inhibitor with anti-tumor activity[1][2].
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BRAF inhibitor | 97.49% | BRAF inhibitor (Compound P-0850) is a B-Raf inhibitor with anti-tumor activity. | ||||||||||||||||||||
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BRAF inhibitor (Standard) | ≥98% | BRAF inhibitor (Standard) is the analytical standard of BRAF inhibitor (HY-10247). This product is intended for research and analytical applications. BRAF inhibitor (Compound P-0850) is a B-Raf inhibitor with anti-tumor activity. | ||||||||||||||||||||
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References
- [1]. Prahbha N. Ibrahim, et al. Pyrrolo[2,3-b] pyridine derivatives as protein kinase inhibitors. WO2007002325A1.
- [2]. Zhang C, et al. Autophagic sequestration of SQSTM1 disrupts the aggresome formation of ubiquitinated proteins during proteasome inhibition. Cell Death Dis. 2022 Jul 15;13(7):615. [Content Brief]
