919482-44-3
Chemical Structure
MK-5757
- CAS No.: 919482-44-3
- Formula:C25H35N3O3
- Molecular Weight:425.56
IUPAC Name: 1-((R)-2,3-dihydroxypropyl)-3-(1-(((1R,3S,4S)-spiro[bicyclo[2.2.1]heptane-2,1'-cyclopropan]-3-yl)methyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
InChIKey: DTAPURRKADLRKH-ZSXPUABSSA-N
SMILES: [H][C@]1(CC2)C[C@]2([H])C3(CC3)[C@H]1CN4CCC(N5C6=CC=CC=C6N(C5=O)C[C@@H](O)CO)CC4
Biological Activity: MK-5757 is a Nociceptin/Orphanin FQ Peptide Receptor antagonist. ORL1 antagonist 3 can improve cerebral blood flow disorders and ischemic damage, and alleviate abnormal neurological symptoms. ORL1 antagonist 3can be used for the research of neurological disease, such as traumatic brain injury[1].
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MK-5757 | MK-5757 is a Nociceptin/Orphanin FQ Peptide Receptor antagonist. ORL1 antagonist 3 can improve cerebral blood flow disorders and ischemic damage, and alleviate abnormal neurological symptoms. ORL1 antagonist 3can be used for the research of neurological disease, such as traumatic brain injury. | |||||||||||||||||||||
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Keywords