920157-23-9
Chemical Structure
MG-V-53
- CAS No.: 920157-23-9
- Formula:C20H17F2N3O2
- Molecular Weight:369.37
IUPAC Name: 2-(4-fluorophenyl)-N-(2-((6-(4-fluorophenyl)pyridazin-3-yl)oxy)ethyl)acetamide
InChIKey: OUJLPIQLWFZGKM-UHFFFAOYSA-N
SMILES: FC1C=CC(C2C=CC(OCCNC(CC3C=CC(F)=CC=3)=O)=NN=2)=CC=1
Biological Activity: MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 value of 121 nM. MG-V-53 has antitumor activity[1].
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MG-V-53 | MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 value of 121 nM. MG-V-53 has antitumor activity. | |||||||||||||||||||||
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Keywords