920650-00-6
Chemical Structure
NCGC00378430
- CAS No.: 920650-00-6
- Formula:C22H23N3O5S
- Molecular Weight:441.50
IUPAC Name: N-(4-methoxy-3-(morpholinosulfonyl)phenyl)-3-(1H-pyrrol-1-yl)benzamide
InChIKey: IFXCVBOQNYHBMX-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(OC)C(S(=O)(N2CCOCC2)=O)=C1)C3=CC=CC(N4C=CC=C4)=C3
Biological Activity:
NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor. NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-β signaling and epithelial-mesenchymal transition (EMT). NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NCGC00378430 | 98.07% | NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor. NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-β signaling and epithelial-mesenchymal transition (EMT). NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model. |
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Keywords
