924-16-3
924-16-3
Chemical Structure
N-Nitrosodibutylamine
Synonym(s): N-Nitroso-di-n-butylamine
- CAS No.: 924-16-3
- Formula:C8H18N2O
- Molecular Weight:158.24
IUPAC Name: N,N-dibutylnitrous amide
InChIKey: YGJHZCLPZAZIHH-UHFFFAOYSA-N
SMILES: CCCCN(CCCC)N=O
Biological Activity: N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water. N-Nitrosodibutylamine regulates caspase pathway. N-Nitrosodibutylamine induces Apoptosis. N-Nitrosodibutylamine induces hepatocarcinoma and oxidative DNA damage[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Nitrosodibutylamine | 99.93% | N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water. N-Nitrosodibutylamine regulates caspase pathway. N-Nitrosodibutylamine induces Apoptosis. N-Nitrosodibutylamine induces hepatocarcinoma and oxidative DNA damage. | ||||||||||||||||||||
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N-Nitrosodibutylamine (Standard) | ≥98% | N-Nitrosodibutylamine (Standard) is the analytical standard of N-Nitrosodibutylamine. This product is intended for research and analytical applications. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water. | ||||||||||||||||||||
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N-Nitrosodibutylamine-d18 | 99.53% | N-Nitrosodibutylamine-d18 is the deuterium labeled N-Nitrosodibutylamine. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water. | ||||||||||||||||||||
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N-Nitrosodibutylamine-d9 | N-Nitrosodibutylamine-d9 is the deuterium labeled N-Nitrosodibutylamine. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water. | |||||||||||||||||||||
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References
- [1]. Chao Zhao, et al. Distribution of N-nitrosamines in Drinking Water and Human Urinary Excretions in High Incidence Area of Esophageal Cancer in Huai'an, China. Chemosphere. 2019 Nov;235:288-296. [Content Brief]
- [2]. García A, et al. N-Nitrosopiperidine and N-Nitrosodibutylamine induce apoptosis in HepG2 cells via the caspase dependent pathway. Cell Biol Int. 2009 Dec;33(12):1280-6. [Content Brief]
- [3]. García A, et al. Organosulfur compounds alone or in combination with vitamin C protect towards N-nitrosopiperidine- and N-nitrosodibutylamine-induced oxidative DNA damage in HepG2 cells. Chem Biol Interact. 2008 May 9;173(1):9-18. [Content Brief]
- [4]. Brittebo EB, et al. Tissue-specificity of N-nitrosodibutylamine metabolism in Sprague-Dawley rats. Chem Biol Interact. 1982 Jan;38(2):231-42. [Content Brief]
- [5]. Dutta S P, et al. Effects of N-Nitrosodibutylamine on the liver mitochondria morphology and on the expression of liver mitochondrial membrane surface proteins in mice. International Journal of Pharmacy and Pharmaceutical Sciences,(8), 2016: 162-168.
