930772-88-6
930772-88-6
Chemical Structure
SAHA-BPyne
- CAS No.: 930772-88-6
- Formula:C27H31N3O5
- Molecular Weight:477.55
IUPAC Name: N1-(4-(4-(hex-5-ynamido)benzoyl)phenyl)-N8-hydroxyoctanediamide
InChIKey: VHTATGLVGGHVIS-UHFFFAOYSA-N
SMILES: O=C(NO)CCCCCCC(NC1=CC=C(C(C2=CC=C(NC(CCCC#C)=O)C=C2)=O)C=C1)=O
Biological Activity: SAHA-BPyne is an activity-based protein profiling (ABPP) probe for detecting HDAC activity, which covalently labels the proximal proteins through a photoactivation. SAHA-BPyne inhibits HDAC activity in HeLa nuclear lysate with an IC50 of less than 5 μM[1].
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SAHA-BPyne | SAHA-BPyne is an activity-based protein profiling (ABPP) probe for detecting HDAC activity, which covalently labels the proximal proteins through a photoactivation. SAHA-BPyne inhibits HDAC activity in HeLa nuclear lysate with an IC50 of less than 5 μM. | |||||||||||||||||||||
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