93674-99-8
93674-99-8
Chemical Structure
RGDV
- CAS No.: 93674-99-8
- Formula:C17H31N7O7
- Molecular Weight:445.47
InChIKey: MDNRBNZIOBQHHK-KWBADKCTSA-N
SMILES: O=C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Biological Activity: RGDV is a platelet aggregation inhibitor. RGDV inhibits platelet-dependent thrombus formation. RGDV is used for tumor recognition via the targeting effect[1][2].
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RGDV | RGDV is a platelet aggregation inhibitor. RGDV inhibits platelet-dependent thrombus formation. RGDV is used for tumor recognition via the targeting effect. | |||||||||||||||||||||
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References
- [1]. Cadroy Y, et, al. RGDV peptide selectively inhibits platelet-dependent thrombus formation in vivo. Studies using a baboon model. J Clin Invest. 1989 Sep;84(3):939-44. [Content Brief]
- [2]. Wang F, et, al. Preparation and biological evaluation of tumor-specific Ara-C liposomal preparations containing RGDV motif. J Pharm Sci. 2012 Dec;101(12):4559-68. [Content Brief]
