93944-58-2
93944-58-2
Chemical Structure
α-Amylase-IN-3
- CAS No.: 93944-58-2
- Formula:C15H9NO4
- Molecular Weight:267.24
IUPAC Name: 4-(2-(4-(5-((3-(4-methylpiperazin-1-yl)quinoxalin-2-yl)thio)-1,3,4-oxadiazol-2-yl)phenoxy)ethyl)morpholine
InChIKey: XJQLOIGEZXCUND-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CC=CC=C2O1)C3=CC=C([N+]([O-])=O)C=C3
Biological Activity: α-Amylase-IN-3 (Compound 4) is the inhibitor for α-Amylase, AChE and AChE with IC50s of 18.04 μM, 21.04 μM and 22.2 μM, respectively. α-Amylase-IN-3 exhibits antioxidant activity. α-Amylase-IN-3 can be used in research of diabetes and oxidative stress associated disease[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
α-Amylase-IN-3 | 99.49% | α-Amylase-IN-3 (Compound 4) is the inhibitor for α-Amylase, AChE and AChE with IC50s of 18.04 μM, 21.04 μM and 22.2 μM, respectively. α-Amylase-IN-3 exhibits antioxidant activity. α-Amylase-IN-3 can be used in research of diabetes and oxidative stress associated disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Na Li, et al. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition. Bioorg Chem. 2020 Nov;104:104208. [Content Brief]
- [2]. Ali I, et al. Benzofuran Hybrids as Cholinesterase (AChE and BChE) Inhibitors: In Vitro, In Silico, and Kinetic Studies[J]. Russian Journal of Bioorganic Chemistry, 2022, 48(6): 1322-1337.
Keywords
