94-15-5
94-15-5
Chemical Structure
Dimethocaine
Synonym(s): Larocaine
- CAS No.: 94-15-5
- Formula:C16H26N2O2
- Molecular Weight:278.39
IUPAC Name: 3-(diethylamino)-2,2-dimethylpropyl 4-aminobenzoate
InChIKey: OWQIUQKMMPDHQQ-UHFFFAOYSA-N
SMILES: CC(C)(COC(C1=CC=C(C=C1)N)=O)CN(CC)CC
Biological Activity: Dimethocaine (Larocaine) is a cocaine derivative and ester-type local anesthetic. Dimethocaine is metabolized by hP450 1A2, 2C19, 2D6, and 3A4 in vitro. Dimethocaine exhibits locomotor-promoting, reinforcing, and anxiogenic effects[1][2].
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Dimethocaine | 99.58% | Dimethocaine (Larocaine) is a cocaine derivative and ester-type local anesthetic. Dimethocaine is metabolized by hP450 1A2, 2C19, 2D6, and 3A4 in vitro. Dimethocaine exhibits locomotor-promoting, reinforcing, and anxiogenic effects. | ||||||||||||||||||||
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References
- [1]. Meyer MR, et al. Dimethocaine, a synthetic cocaine derivative: studies on its in vitro metabolism catalyzed by P450s and NAT2. Toxicol Lett. 2014;225(1):139-146. [Content Brief]
- [2]. Rigon AR, et al. Stimulant activities of dimethocaine in mice: reinforcing and anxiogenic effects. Psychopharmacology (Berl). 1996;127(4):323-327. [Content Brief]
Keywords
