941521-45-5
941521-45-5
Chemical Structure
BAZ1A-IN-1
- CAS No.: 941521-45-5
- Formula:C16H12N4O3S
- Molecular Weight:340.36
IUPAC Name: 1-(3-nitrophenyl)-3-(4-phenylthiazol-2-yl)urea
InChIKey: UJRJAZDAWUSWRK-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC([N+]([O-])=O)=C1)NC2=NC(C3=CC=CC=C3)=CS2
Biological Activity: BAZ1A-IN-1 is a potent inhibitor of BAZ1A (bromodomain-containing protein). BAZ1A-IN-1 shows a KD value of 0.52 μM against BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-viability activity against cancer cell lines expressing a high level of BAZ1A, but weak or no activity against cancer cells with a low expression level of BAZ1A[1].
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BAZ1A-IN-1 | 99.91% | BAZ1A-IN-1 is a potent inhibitor of BAZ1A (bromodomain-containing protein). BAZ1A-IN-1 shows a KD value of 0.52 μM against BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-viability activity against cancer cell lines expressing a high level of BAZ1A, but weak or no activity against cancer cells with a low expression level of BAZ1A. | ||||||||||||||||||||
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