941580-60-5
941580-60-5
Chemical Structure
NVS-PI3-4
- CAS No.: 941580-60-5
- Formula:C20H26N4O3S
- Molecular Weight:402.51
IUPAC Name: 3-(3-(5-(4-acetylphenyl)-4-methylthiazol-2-yl)ureido)-N-(tert-butyl)propanamide
InChIKey: IUPXLLWDLOWEBR-UHFFFAOYSA-N
SMILES: O=C(NC(C)(C)C)CCNC(NC1=NC(C)=C(C2=CC=C(C(C)=O)C=C2)S1)=O
Biological Activity: NVS-PI3-4 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NVS-PI3-4 | 99.40% | NVS-PI3-4 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases. | ||||||||||||||||||||
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References
- [1]. Bruce I, et al. Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway. Bioorg Med Chem Lett. 2012;22(17):5445-5450. [Content Brief]
- [2]. Collmann E, et al. Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy. J Allergy Clin Immunol. 2013;132(4):959-968. [Content Brief]
Keywords
