942142-51-0
942142-51-0
Chemical Structure
VTP-27999
- CAS No.: 942142-51-0
- Formula:C26H41ClN4O5
- Molecular Weight:525.08
IUPAC Name: methyl (2-((R)-(3-chlorophenyl)((R)-1-(((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propyl)carbamoyl)piperidin-3-yl)methoxy)ethyl)carbamate
InChIKey: NXWASIVXQMMPLM-ZXMXYHOLSA-N
SMILES: O=C(N1CCC[C@@H]([C@@H](OCCNC(OC)=O)C2=CC=CC(Cl)=C2)C1)NC[C@@H](NC)C[C@@H]3COCCC3
Biological Activity:
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VTP-27999 | VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases. | |||||||||||||||||||||
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References
- Lanqi Jia et al. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility ACS Med. Chem. Lett., 2011, 2 (10), pp 747-751
- New renin inhibitor VTP-27999 alters renin immunoreactivity and does not unfold prorenin. Hypertension. 2013 May;61(5):1075-1082. [Content Brief]
