947540-06-9
Chemical Structure
MAO-B-IN-51
- CAS No.: 947540-06-9
- Formula:C15H16F3N3O2S
- Molecular Weight:359.37
IUPAC Name: (4-hydroxypiperidin-1-yl)(5-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)thiophen-2-yl)methanone
InChIKey: WAPUAZWMCBAXGP-UHFFFAOYSA-N
SMILES: O=C(C=1SC(=CC1)C2=NN(C(=C2)C(F)(F)F)C)N3CCC(O)CC3
Biological Activity: MAO-B-IN-51 (Compound 8f) is a selective, blood-brain-barrier permeable, orally active MAO-B inhibitor with an IC50 of 48.9 nM (MDS). MAO-B-IN-51 enhances long-term memory[1].
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MAO-B-IN-51 | MAO-B-IN-51 (Compound 8f) is a selective, blood-brain-barrier permeable, orally active MAO-B inhibitor with an IC50 of 48.9 nM (MDS). MAO-B-IN-51 enhances long-term memory. | |||||||||||||||||||||
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Keywords