948845-91-8
948845-91-8
Chemical Structure
ABT-288
- CAS No.: 948845-91-8
- Formula:C23H24N4O
- Molecular Weight:372.46
IUPAC Name: 2-(4'-((3aR,6aR)-5-methylhexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)-[1,1'-biphenyl]-4-yl)pyridazin-3(2H)-one
InChIKey: GNIRITULTPTAQW-KNQAVFIVSA-N
SMILES: CN1C[C@]2([H])N(C3=CC=C(C4=CC=C(N5C(C=CC=N5)=O)C=C4)C=C3)CC[C@]2([H])C1
Biological Activity: ABT-288 is a competitive, potent and selective histamine H3 receptor (H3R) antagonist. ABT-288 has Ki values of 1.9 and 8.2 nM for human and rat H3Rs, respectively. ABT-288 can be used in cognitive impairment research.[1].
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ABT-288 | ABT-288 is a competitive, potent and selective histamine H3 receptor (H3R) antagonist. ABT-288 has Ki values of 1.9 and 8.2 nM for human and rat H3Rs, respectively. ABT-288 can be used in cognitive impairment research.. | |||||||||||||||||||||
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References
Keywords
