949099-81-4
Chemical Structure
(S)-PF-04445597
- CAS No.: 949099-81-4
- Formula:C29H31F9N6O2
- Molecular Weight:666.59
IUPAC Name: (S)-1-(1-(2-(((3,5-bis(trifluoromethyl)benzyl)(2-methyl-2H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-methylpropyl)piperidine-4-carboxylic acid
InChIKey: DZNFADLAFQEDJQ-DEOSSOPVSA-N
SMILES: [C@H](C(C)C)(C1=C(CN(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C=3N=NN(C)N3)C=C(C(F)(F)F)C=C1)N4CCC(C(O)=O)CC4
Biological Activity: (S)-PF-04445597 is an orally active cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 0.07 μM. (S)-PF-04445597 inhibits CETP-mediated transfer of cholesteryl esters from HDL to non-HDL lipoproteins. (S)-PF-04445597 can be used for research on coronary heart disease[1].
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(S)-PF-04445597 | (S)-PF-04445597 is an orally active cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 0.07 μM. (S)-PF-04445597 inhibits CETP-mediated transfer of cholesteryl esters from HDL to non-HDL lipoproteins. (S)-PF-04445597 can be used for research on coronary heart disease. | |||||||||||||||||||||
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