950381-32-5
950381-32-5
Chemical Structure
PPQ-581
- CAS No.: 950381-32-5
- Formula:C25H24FN3O3
- Molecular Weight:433.47
IUPAC Name: 10-(2-fluorophenyl)-1,3,7,7-tetramethyl-5-phenyl-1,7,8,10-tetrahydro-2H-pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]oxazine-2,4(3H)-dione
InChIKey: FTIYTQDSSDROKM-UHFFFAOYSA-N
SMILES: O=C1C2=C(N3C(C(C4=C(F)C=CC=C4)OCC3(C)C)=C2N(C)C(N1C)=O)C5=CC=CC=C5
Biological Activity: PPQ-581 is an anti-influenza agent with an EC50 of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation[1].
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PPQ-581 | PPQ-581 is an anti-influenza agent with an EC50 of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation. | |||||||||||||||||||||
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References
Keywords
